Anadrol Oxymetholone is a powerful oral steroid for increasing size and strength.
People have reported massive weight orgains of over 30lbs in one cycle, but it’s not without its downsides.
As a 17-α-alkylated oral anabolic-androgenic steroid, it’s been altered at the 17th carbon position in order to survive its first pass through the liver.
Although this is necessary for the steroid to work, it also means it’s very toxic to the liver, one of the worst steroids out there.
Although there is no progestational activity, it still causes estrogenic side effects like gynecomastia and water retention – leading to high blood pressure. It’s also known to cause really bad headaches.
The steroid guru Dan Duchaine promoted it as a cheaper alternative to Dianabol for bulking cycles, but its side effects are also considered to be much worse. Buy Anadrole online here.
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Anadrol, also known as Oxymetholone, Anapolon, A50, or A-Bombs, is a synthetic and orally active 17α-methylated derivative of dihydrotestosterone (DHT derivative).
It was developed in the 1960s under the brand name Anadrol 50 Oxymetholone to help people with anemia.
Oxymetholone promotes increased protein synthesis, a higher red blood cell count, and increased appetite, which is why athletes and bodybuilders take to it.
Compared to testosterone, it has a very high anabolic rating of 320 and a very low androgenic rating of 45.
That means Anadrol doesn’t bind well to the androgen receptor, but can still cause many androgenic side effects such as male pattern baldness, body hair growth and acne.
It’s also enough for it to be a bad choice for female bodybuilders to take, due to the virilization symptoms that will occur.
Most Anadrol tablets are 50mg in size. With a half-life of about 8 hours, you should take this drug daily.
For entry level cycles and people just starting up with Anadrol, it usually is recommended to begin at 25mg a day. Just split the tablet in half.
Although most men do take 50mg per day, it’s probably better to start low and build your way up.
Move up to 50 during the six week cycle if you want. For the most experienced users, hitting up to 100mgs a day is possible, although it should not be pushed more than this per day.
After that, the additional benefits drop off but the side effects become almost guaranteed.
Either way, the 50mg amount does make it easy to measure the proper dosage amount and to stay on a quality cycle without accidentally taking too much or not enough on a daily basis.
The pills form is considered superior to the liquid gel form as it is easier to measure out the dosage.
The liquid gel is prescribed to farm animals in order to boost muscle growth, making the animals larger so the farmers can sell the cows for more money based on the weight gains.
Liquid Anadrol is going to vary form one manufacturer to the next and it is necessary to look up the ml to mg dosage amount, which can become confusing.
The last thing anyone should worry about becoming confused about is the amount of steroid they are taking on a daily basis.
How long is a cycle of Anadrol? Anadrol cycles should not exceed 4-6 weeks.
It is typically stacked with some form of exogenous Testosterone. Like most anabolic-androgenic steroids, Anadrol will cause the suppression of natural testosterone production in the body, leaving you with low levels of this androgen hormone.
For that reason, many bodybuilders will use drugs for testosterone replacement therapy during their cycle. You could stack with 750mg of Sustanon per week.
Some of the forms of testosterone used by bodybuilders, including:
Anadrol is considered one of the harshest steroids on the market. Despite a low androgenic rating, it still causes acne, hair loss, and body hair growth.
It’s hepatoxicity is high, meaning it’s hard on the liver. Use must be limited to 4-6 weeks because of this. You also need to avoid use of alcohol while on this steroid.
Gynecomastia and water retention will occur despite there being no progestational activity, as a result high blood pressure can occur.
Testosterone suppression is to be expected, and low testosterone will result unless you combine with exogenous testosterone like Andriol Testocaps or Testosterone Enanthate.a
It will also lower good cholesterol (HDL) and may increase bad cholesterol (LDL). If you already have bad cholesterol, you shouldn’t be using this steroid.
Peliosis hepatis (often wrongly written as peliosis hepatitis), a condition where the liver is replaced with blood-filled cysts has occurred in patients using steroids in general.
The high risk of liver toxicity means that it should only be used in very short cycles of no longer than 4-6 weeks at a time.
The harsh adverse effects are not limited to hepatotoxicity, though, and some of the more serious side effects of Anadrol are not yet understood.
Like some anabolic-androgenic steroids, Anadrol is unable to interact with the aromatase inhibitor responsible for converting Testosterone into Estrogen. Despite this, the drug displays significant estrogenic activity.
Another side effect that is not well understood is that, despite having an androgenic rating of 45, significantly lower than that of Testosterone, it causes very strong androgenic side effects in some users.
Because of these negative effects, it should only be used by more experienced anabolic steroid users and should be avoided by beginners.
Estrogenic Side Effects of Anadrol
Anadrol increases Estrogen levels significantly. Unlike other anabolic steroids with strong Estrogenic activity, however, this is not due to the steroid being converted into Estrogen, as it is chemically incapable of such a conversion due to its inability to interact with the aromatase enzyme.
Because of this, the estrogenic effects are still a mystery, but some experts believe that Anadrol may mimic Estrogen in some tissues.
Another theory suggests this reaction is actually due to progestogenic activity, similar to that seen in Nandrolone.
However, at least one study on the progestogenic potential of Anadrol showed that it possesses no progestogenic activity whatsoever, thereby disproving this idea.
Regardless of the reason why Anadrol has such high Estrogenic activity, side effects of this include: bloating, fat gain, and swollen breast tissue (gynecomastia).
Because the estrogenic effects are not due to direct conversion by the aromatase enzyme, aromatase inhibitors are of no help in mitigating these side effects.
The risks can be somewhat reduced by dietary adjustments, but even with good diet, excess water weight is still likely to be a problem for most users.
Gynecomastia can be effectively managed with the use of a Selective Estrogen Receptor Modulator (SERM). SERMs, such as Nolvadex, are a class of drugs that block Estrogen from binding to the receptors in breast tissue.
It is important to remember, however, that these drugs only prevent the effects of Estrogen on breast tissue and will not affect the action of Estrogen in the rest of the body, which is why water retention remains a problem with Anadrol.
Androgenic Side Effects
With an androgenic rating of 45 compared to Testosterone’s rating of 100, Anadrol is technically a bit less than half as strong an androgenic steroid as Testosterone. Despite this, it can still cause significant androgenic side effects.
Some Anadrol users have even reported experiencing androgenic side effects far stronger than such a low rating would indicate.
As a DHT derivative, this compound does not interact with the 5-alpha reductase enzyme and would not be expected to convert to Dihydrotestosterone. However, it is created by the addition of a 2-hydroxymethylene group to DHT.
As Anadrol is metabolised by the body, this 2-hydroxymethylene group is removed, leaving behind a form of DHT known as 17-alpha-methyl dihydrotestosterone, or Mestanolone.
What this means is that, Anadrol is different from most DHT derivatives in that it can be converted into DHT, this conversion simply happens by a different mechanism than is seen in other steroid families.
This form of DHT has an androgenic rating of between 78 and 254, much higher than Anadrol and even Testosterone. It is this conversion that is thought to cause androgenic side effects in some users so much stronger than would otherwise be expected from Anadrol.
Such side effects include: excess sebum production leading to oily skin and acne breakouts, excess body and facial hair, and Male Patter Baldness in individuals with a genetic predisposition to the condition.
HPTA and Endogenous Testosterone Production Side Effects
All anabolic steroids have the potential of suppressing, and even halting, natural Testosterone production in the body.
Not only is Anadrol not an exception to this rule, the post-cycle crash of Anadrol can be one of the worst seen among anabolic steroid users. This is due to the way in which Anadrol works in the body.
Anadrol is known for dramatically increasing body mass very quickly, partly due to significant water retention. At the end of an Anadrol cycle, much of that mass is lost just as quickly as excess water is released from the tissue.
Gains in muscle mass achieved through the use of Anadrol can, at least in part, be maintained through the use of powerful Post Cycle Therapy (PCT) with compounds designed to stimulate the body to resume producing Testosterone naturally.
Hepatotoxic Side Effects
Of all the side effects Anadrol is known for, the number one issue for many users is the hepatotoxic nature of the steroid.
The method of producing Anadrol through the process of C17-Alpha Alkylation has already been discussed as a primary factor in the hepatotoxic side effects seen in Anadrol.
In an attempt to make Anadrol less hepatotoxic, it is synthesized with a saturated A ring. However, Anadrol seems to defy this attempt at mitigating its side effects as seen by the results of several studies.
In one study, 31 male patients who had tested positive for HIV were given 50-100mg of Anadrol per day for 12 weeks.
Significant increases in y-glutamyltransferase (GGT) were seen in 17% of test subjects, bilirubin increased in 10% of subjects, and 20% of test subjects had increased serum albumin.
In addition, many Anadrol users have been diagnosed with peliosis hepatis, a serious and potentially life-threatening vascular condition characterised by blood-filled cavities in the liver ranging in size from a few millimeters to three centimeters.
To prevent this, Anadrol users are strongly advised to limit cycles to 4-6 weeks at a time and to supplement with liver support compounds such as TUDCA/UDCA during cycles.
Cardiovascular Side Effects
Another serious side effect of Anadrol is cardiovascular strain. Anabolic steroids, and especially those intended for oral administration, are well known for causing harmful changes in cholesterol levels, both in decreasing HDL (good) cholesterol, and increasing LDL (bad) cholesterol.
These changes increase risk of developing arteriosclerosis. These negative changes in cholesterol levels, and the resulting risk of arteriosclerosis, tend to be dose dependent.
This not only means that the risk increases as dosage increases, but also means that risk increases the longer Anadrol is used.
In addition, oral steroids such as Anadrol demonstrate this effect more notably than to injectable steroids. This is due to the liver’s role in processing cholesterol for use in the body and the hepatotoxic nature of oral anabolic steroids.
These effects are even strong with Anadrol than with many other anabolic steroids because it tends to resist breakdown by the liver.
In studies on men given 50-100mg of Anadrol per day for 12 weeks have experienced dangerous increases of LDL levels and decreases in HDL levels of 19-23 points.
Because of all of these potential side effects, it is important to not just include liver supporting supplements during steroid cycles, one should also use supplements that support the cardiovascular system and follow a diet that promotes healthy cholesterol levels.
It is also important to have cholesterol levels and liver enzymes checked on a regular basis.
Anadrol tablets are approved by the FDA for the treatment of anemia. But as a bodybuilder, it’s unlikely you’ll get a prescription for them.
Without one, you won’t be able to pick it up at your local pharmacy.
That means you’ll likely have to buy Anadrol steroids over the Internet or from an underground lab.
Knowing what to look for and how to find the best tablets that provide the highest quality results is important, but it is possible to sort through the inferior sales sites to locate the best options out there.
When shopping around for Anadrol pills online, there are a few different aspects to always keep in mind. The most important is the quality of the source.
While the product might say “Anadrol” on the label, it does not mean it is going to have the same high quality content as another steroid for sale. There are lots of fakes out there, up to 53% of steroids bought online were fake in one study.
The manufacturing locations are not strictly monitored inside of India and China, which means the finished product it not going to be of the highest quality, and it also might not contain the stated amount of the steroid.
If the drug has a higher potency of the steroid, it is going to cause possible health problems later on down the road.
There is also the chance that the drug doesn’t have the steroid in it at all, which means the buyer is just going to be spending a large sum of money on Anadrol steroids that don’t work at all.
Although people trust Oxydrol British Dragon or Anadrol Oxyanabolic by Asia Pharma because they are recognizable brand names and reviews say they won’t be fake, they still might be.
There are cheaper generic versions as well but you don’t know what you’re going to get.
Anadrol should cost around $60-80 for 100 pills, but could be as high as $150-200.
Other brands available include:
Most Anadrol comes in blue pills that are hexagon shaped (not to be confused with Dianabol Blue Hearts).
There are some ways to identify these possible companies in order to identify the better sales providers in lesser known regions (Eastern Europe) and that is through direct reviews listed on bodybuilding and weight loss forums.
The forums can include insights from individuals who have cycled on Anadrol 50 tablets, purchased the product from different websites and testing out not only the tablet form but liquid gel form as well.
These experienced individuals can point to the best locations to buy the drugs, the best way to go about cycling and the results to expect.
As it is not generally possible to sit down and talk over steroid dosing with a doctor, the next best thing is to discuss the steroids with users who have extensive experience using Anadrol.
Chances are, the product is going to come from an international location if you’re finding Anadrol for sale online. International shipping is not an issue from the seller as most locations understand the majority of clients come from overseas.
The problem is when you try to import it. Depending on which country you live in, there are differing import laws and penalties that can range from being allowed to import small amounts for personal possession like in the UK to huge fines and jail time in Australia.
For anyone looking to start up on an Anadrol cycle, Anadrol tablets remain the most common form of the steroid.
So, whether someone is starting out on a 25mg a day cycle or they are more experienced and looking to begin an eight week, 100mg a day cycle, you should know everything you can about this oral steroid before taking it. Know how it increases red blood cell count to how it could cause male pattern baldness.
17β-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one is the scientific name for Anadrol Oxymetholone and its molecular formula is C21H32O3. Make sure you do your homework and know all the risks before taking this drug to gain muscle mass.
Alternatives like Liquid Anodrol Oxymethobol or CrazyBulk’s Anadrole can also help with strength, muscle growth and weight gain. Anadrole increases red blood cell production and the company claims you’ll see before and after results within 30 days – all without the risk of side effects.