Drostanolone (Masteron) is an anabolic androgenic steroid.
It is used by bodybuilders in cutting cycles.
It is known by many chemical names depending on manufacturer and country of origin.
Some of them include:
Before using any synthetic anabolic androgenic steroid for bodybuilding benefits, it’s important to be aware of what it is and how it works in the body.
What can a bodybuilder or athlete expect in regard to Drostanolone results? Buy legal steroids online here.
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The similarity between the many of these names can be confusing.
It is easily recognized by its chemical or molecular formula: C20H32O2.
Drostanolone is similar in effect to its relationship to dihydrotestosterone.
Dihydrotestosterone is a metabolite of testosterone and has potent anabolic and effects on the body.
This steroid does not tend to trigger estrogenic properties but at the same time can contribute to virilism in women.
In medical scenarios, Drostanolone has been used to reduce the growth of estrogen receptors for women diagnosed with breast cancer, but it’s negative side effects (the virilism) more often than not outweigh its benefits.
One of the main mechanisms of action of Drostanolone is its ability to target and bind to androgen receptors.
This linkage contributes to a number of benefits for bodybuilders and athletes, including but not limited to:
Drostanolone is a base drug that can be slightly modified due to attachment of specific esters.
For example, Drostanolone propionate 100mg, otherwise known by the brand name Masteron, is a commonly used injection form of the anabolic androgenic steroid.
You cannot buy Drostanolone oral tablets, this is because it is not orally active, and therefore it is only sold as an injection.
Masteron/drostanolonum, is reputed to be a relatively gentle synthetic anabolic androgenic steroid that is more commonly used in cutting or dieting phases.
Such usage promotes the development of lean muscle mass without the often-negative side effects associated with other more potent steroids that cause negative estrogenic influences on the body including:
Drostanolone with different esters can influence not only its absorption rate into the body, but also how long it lasts in the body, known as its half-life.
For example, Drostanolone (propionate) has a relatively short half-life, averaging 48 hours following injection.
Masteron cycles are considered to be limited by a narrow set of applications for performance users.
The compound is not observed to be favorable for strength gain or bulking.
There are also anabolic steroids that are held to be better and more cost-effective than Masteron for fat loss or cutting.
Masteron cycles tend to be very niche, used primarily by professional bodybuilder for pre-contest and fat-loss cycles.
In these cycles, Masteron is usually an add-on, not the major compound involved in fat loss or cutting.
The length of a typical Masteron cycle is 8-10 weeks.
Some bodybuilders will cycle Masteron only during the last 2 to 4 weeks of a cycle leading up to a photo-shoot or show. This is to gain the benefit of its physique enhancement abilities without breaking the bank due to its high cost.
Generally, a cycle like this is performed for 10 weeks, often with the use of compounds like Trenbolone Acetate, Testosterone Propionate, and Anavar.
Masteron is included into the mix towards the 6 or 8-week mark of the cycle, and is used till the end of the 10th week.
Some physique builders also attempt to use Masteron as a fat loss or cutting compound, engaging in consistent use for a period of 8-10 weeks along with other compounds of the same nature like injectable Testosterone Propionate, Winstrol and Trenbolone Acetate.
No medically recommended dosage criteria are available for Drostanolone.
A common dosage range for body enhancement starts at 200 mg a week but can range up to 400 mg a week.
Always start at the lowest dosage possible to gauge how the body reacts to it and to reduce the potential for negative side effects.
Side effects are always possible with any drug.
This is especially true when using a synthetic anabolic androgenic steroid without a prescription or supervision by a physician.
Even though this component is reputed to have relatively low androgenic properties, the risk of androgen side effects does increase as dosage increases.
In some cases, use of Drostanolone can cause weight gain. While most bodybuilders are aware that this weight gain is caused by fluid retention rather than increased muscle mass or strength, they don’t seem to care.
Other negative side effects are also possible, including:
Testicular atrophy or shrinking testicles that is caused by the lack of natural testosterone production in the body.
If the gland is not used – in this case the testes – it decreases in size. This can contribute to a decrease in sperm production, sperm quality, and fertility.
Liver damage – not always dosage dependent or associated with long-term use, anabolic androgenic steroids can have negative impact on liver functions and contribute to a condition known as Hepatis peliosis.
This condition defines the development of cysts filled with blood inside the liver. If these cysts burst, internal hemorrhaging is a likely possibility.
Negative impact on serum cholesterol levels – steroids like Drostanolone can have a negative impact on otherwise normal balances of high-density lipoprotein and low-density lipoprotein in the body.
Such imbalances can increase the risk for development of atherosclerosis or build-up of plaque inside the arteries that disrupts blood flow. This can contribute to heart attack or stroke.
Drostanolone tends to trigger virilism (virilization) or masculine trait characteristic development in women. In some cases, multiple symptoms associated with Drostanolone and virilism are irreversible:
Women who are pregnant, planning to become pregnant, or nursing should avoid use of any drugs, especially anabolic androgenic steroids due to their potential to disrupt normal fetal development during pregnancy.
Drostanolone is not cycled for mass gains, but to harden and enhance an already built physique.
Masteron’s specific name is Dromostanolone (the abbreviated name given after its release is Drostanolone).
As we’ve mentioned earlier, it’s a synthetic variation of DHT, which is known as Dihydrotestosterone.
Drostanolone is a derivative of DHT with a methyl group added at the 2nd carbon atom.
The slight lift in anabolic strength that can sometimes be observed when compared with Testosterone is the result of the modification.
The addition of the methyl group enhances the anabolic potency by increasing the capacity of Masteron to resist conversion into an idle metabolite through contact with the 3-hydroxysteroid dehydrogenase enzyme.
A high quantity of this enzyme exists in muscle tissue, and it is responsible for converting any DHT that enters the muscle tissue into two different inactive metabolites: 3-Beta Androstanediol and 3-Alpha Androstanediol, both of which are non-anabolic.
This is the main reason why DHT is not anabolic within the muscle tissue, despite reportedly being 3-4 times stronger than testosterone.
Some biologists and chemists are of the opinion that without the the presence of 3-hydroxysteroid dehydrogenase within the muscle tissue, the DHT would be a much more results-driven anabolic steroid.
Masteron has effectively overcome the problem of being metabolized by the enzyme with the presence of an added methyl group to the alpha carbon 2.
Two variants of Masteron exist: Drostanolone Enanthate and Drostanolone Propionate. The more famous one of the two is the Propionate variant.
Propionate is a Propanoic acid but upon being attached to Masteron, it is referred to as an ester linkage or bond.
On the Drostanolone chemical structure, Propanoic acid is attached to the 17-beta hydroxyl group.
The hormone’s half-life as well as release rate is altered when this ester is added, thus providing a longer release window.
The increase of its rate of release and half-life is the time it takes for the bond between the hormone and the ester to be broken down by the enzymes in the body when Drostanolone Propionate goes into the blood stream.
All esters extend the release rate of the drugs they are attached to in this way, but the duration of time can vary depending on the ester.
When the enzymes succeed in removing the ester from the hormone, pure Masteron is left to work within the body.
Propionate-esterified Drostanolone has a half-life of 2.5 days, while Drostanolone Enanthate has a half-life of 10 days.
Esterification does not alter the mechanism of action of the hormone. Apart from extending the release window, esters do not change any characteristics of the steroid to which they are bound.
Drostanolone Enanthate is similar to Masteron (Drostanolone Propionate) and is sold on the underground market only.
Masteron is not popular like other anabolic steroids.
It is available through some vendors online. Masteron is thought to be an expensive anabolic steroid, and this true for the products manufactured by underground laboratories.
Pharmaceutical grade Masteron is rare, and some physique builders believe it does not exist.
Masteron is only available for sale as an underground lab (UGL) product. Dromostan is the only pharmaceutical grade Drostanolone product which exists today, and it is manufactured by Xelox Company out of Mayanmar.
However, this product is neither Drostanolone Enanthate nor Propionate. It is a Drostanolone base which is a non-esterified variant of Drostanolone.
This is considered to be a useless product to most bodybuilders and athletes. According to bodybuilders, the short half-life means an injection would be needed at least once on a daily basis.
Multiple injections per day would likely be required to gain any result.
Depending on the source from which Masteron is bought, price of UL grade Masteron can range from $170-$230 for a 10ml container which has a concentration of 100mg/ml.
There are some cheap sources which may have Masteron available at a price ranging from $80-$120 in the same concentration.
Drostanolone may be effective for men and women in regard to their physique improvement, but what it can do to internal organs and systems should never be ignored.
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