GHRP-6 stands for growth hormone releasing peptide. The '6' defines it as six-sided or a hexapeptide.
GHRP stands for Growth Hormone Releasing Peptide. It is classified as a protein or peptide hormone.
This Growth Hormone Releasing Hexapeptide falls in the group of compounds called Human Growth Hormone (HGH) secretagogues. This means that the secretion of HGH is stimulated by peptide hormones.
Moreover, GHRP-6 falls into the sub-category of HGH secretagogues called Ghrelin mimetics, comprised of various Growth Hormone Releasing Hormone (GHRH) analogues.
When looking for information about the hormone, your search will bring up dozens of bodybuilding websites.
What does it have to do with bodybuilding? Why would a bodybuilder or athlete use it? Buy HGH-X2 online here.
Table of Contents
Growth hormone releasing peptide (6) is a chemical compound manufactured by a number of bioscience research companies around the world.
Peptides like GHRP-6 or others like Sermorelin GHRP2 are popular among bodybuilders who inject growth hormone releasing peptides into their body.
It helps to enhance muscle growth by increasing synthesis of growth hormone.
Growth hormone is manufactured in the body’s pituitary gland, located in the brain.
To enhance this production and secretion, exogenous (outside the body) drugs such as growth hormone releasing peptides are utilized by bodybuilders.
This hormone is chemically called L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-Lysinamide with a chemical formula C46H56N12O6 and molecular mass 873.014g/mol.
Other peptides classified as Ghrelin mimetics are GHRP-2, Ipamorelin and Hexarelin.
These are called Ghrelin mimetics due to the fact that they imitate the actions of the endogenous hormone Ghrelin, attaching themselves to the growth hormone secretagogue receptor which is located at the anterior pituitary gland.
Ghrelin also functions as a peptide hormone that stimulates hunger, and this explains why many GHRPs can stimulate appetite at different levels or degrees.
Furthermore, GHRP-6 and other Ghrelin mimetics mentioned earlier are different protein/peptide hormones from GHRH, which include GRF 1-29 and CJC-1295 without DAC.
Growth Hormone Releasing Hormones (GHRH) such as CJC-1295 are different growth hormone secretagogues that function via different receptors and pathways. GHRP and GHRH are not synonymous.
In the body, natural production and secretions of growth hormone trigger the release of insulin like growth factor-1 (IGF-1) another type of hormone produced and secreted by the liver.
Growth hormone and IGF-1 are the two main hormones associated with accelerated muscle growth, both medically speaking and in the world of bodybuilding.
Testosterone is another hormone often combined with growth hormones or IGF-1 to accelerate and enhance benefits.
Growth hormones and insulin-like growth factor-1 can make the muscles grow, but it’s the testosterone that will make muscles stronger.
Other benefits of GHRP-6 is that it can aid in weight loss and fat loss. This is because it mimics the effects of ghrelin, yet another hormone produced in stomach cells.
Ghrelin is most commonly known as the “hunger hormone” that influences body weight depending on fat levels in the body.
Bodybuilders who don’t want to risk the side effects of exogenous growth hormone often turn to GHRPs such as GHRP-6 or GHRP-2.
If you don’t understand chemistry, you might be thinking that it doesn’t seem like a huge difference between GHRP-6 vs 2, but there is.
GHRP-6 doses are often used in conjunction with GHRH analogues like Mod GRF 1-29, also referred to as CJC-1295 without DAC.
Synergistic properties exist between these two compounds. However, GHRP-6 doses remain the same whether they are used on their own or utilized with GHRH.
The GHRP-6 100 mcg dose is thought to be efficient even if it is administered individually or in combination with the Mod GRF 1-29.
The term “saturation dose” is commonly used when discussing peptides. A saturation dose can be defined as the dose that that almost completely or totally saturates the target receptors of the peptide.
In case of the GHRP-6 the receptors are the Ghrelin receptors which are located in the anterior pituitary and hypothalamus.
Based on studies conducted on this topic, the saturation dose of GHRP-6 is considered to be around 1 mcg per kilogram of the body weight and the average dosage of approximately 100 mcg can be taken to achieve the same result without calculating bodyweight.
This means that a 100 mcg saturation dosage of GHRP-6 is taken to fully saturate the receptors.
Increasing it to 200 mcg is believed to only provide an additional 50% effectiveness, and 300 mcg only an additional 25% from there.
This pattern is held to continue for larger doses. This is felt to apply to almost all peptide of this nature, whether GHRPs and GHRH analogues.
The main concern with GHRP-6 doses (or virtually any Ghrelin mimetic doses) is that it is reported to induce a higher than normal secretion of Prolactin and Cortisol.
This has been demonstrated in many studies, but the test subjects who used doses of GHRP-6 that were 100 mcg or lower were reported to experience no difference in their Cortisol and Prolactin levels.
The dose of GHRP-6 that is over 100 mcg is suggested to result in minimal secretion of Prolactin and Cortisol.
Increasing the dosage even more will take the Cortisol and Prolactin secretion levels higher.
The measurement unit for GHRP-6 doses is microgram or mcg, and there is a distinction between the measurement units used for different performance enhancing drugs which are often given in milligrams or mg.
Synthetic HGH or Human Growth Hormone on the other hand are measured in international units or IU.
Artificial HGH and HGH inducing compounds like GHRP-6 are typically used for cycles lasting anywhere from 4-6 months.
The main reason why is because, naturally-speaking, Human Growth Hormone is a hormone that exerts gradual and progressive changes on the system and body formation.
Many alterations may occur sooner while other changes like significant muscle growth and strength increases can take a few months to develop.
GHRP-6 cycles aimed at muscle gain and fat burning often incorporate dosages of 100mcg at least 3 times daily for 4-6 months.
Some physique builders recommend users exceed even this dosage and administer 4-5 injections daily for more substantial lean muscle gain. These GHRP-6 dosage cycles would ensure a constant supply of HGH that would reach the levels that might be experienced with cycling Somatropin.
GHRP-6 cycles with the aim of fat loss are believed to require an approximate dose of 100mcg of the compound 2-3 time every day for a period of 4 to 6 months.
Experienced peptide users will say this can leave room for minor lean muscle mass gains in a few cases, as long as diet and training regimes are geared towards this effect.
Finally, rejuvenating and anti-aging cycles of GHRP-6 are said to require 1 to 2 injections every day dosed at 100mcg for each use.
This limited administration plan of GHRP-6, like the one above, is cycled with the hopes of contributing to the secretion of enough HGH from the pituitary gland to achieve anti-aging and regenerative effects.
GHRP-6 cycles will also commonly stack a GHRH compound like Mod GRF 1-29 in order to reach higher HGH levels.
GHRP is also stacked with anabolic drugs—similar to how artificial HGH is paired with anabolics—to complement the drugs on the level of muscle mass gain and fat loss.
Somatropin can be stacked with other HGH inducers like GHRP-6, which are taken to raise HGH levels in the blood plasma of the user without having to use high levels of synthetic HGH.
Bodybuilders will often dose exogenous artificial HGH compounds right after waking-up in the morning, followed by doses of GHRP-6 at noon, with an extra optional dose of Somatropin half an hour after the dose of GHRP-6. Lastly, an extra dose of GHRp-6 might be taken right before sleeping.
This GHRP-6 cycle is taken to maximize the effects of HGH. It is also known to be much more cost-efficient than taking only HGH doses.
An added advantage is thought to be the potential for the user to keep an active pituitary gland function upon the use of artificial HGH, which would typically lead to a pause of internal HGH secretion.
The administration of HGH inducers like GHRP-6 before sleep time are believed in bodybuilding circles to ensure the ongoing secretion of internal HGH by the pituitary gland.
GHRP-6 is an injectable drug commonly sold in 5 mg vials. Bodybuilders typically use insulin syringes to inject a dosage in a variety of methods:
Guidelines for the use may vary slightly depending on bodybuilding website information or discussions by bodybuilders who use GHRP-6 cycles in their routines. Most recommend taking it thirty minutes to one hour before a meal.
What GHRP-6 dosage to take? Recommendations differ. Some users find that injections of 50 mcg two or three times a day is efficient while others inject as much as 300 mcg at one time.
Dosage and guidelines for use may also depend on what other drugs are stacked with the GHRP-6.
Some bodybuilders combine the growth hormone releasing peptide with growth hormone releasing hormone (synthetic). In such cases, dosages may need to be adjusted.
Most functions in the body are connected in some way. For example, amino acids are required for the manufacture of protein.
Amino acids are considered literal building blocks – the foundation of protein synthesis.
Amino acids utilize nitrogen and oxygen in this protein-building process. Protein is required not only for muscular growth, but for life in all cells in the body. Protein can be found not only in muscle, but:
Proteins are essential in regulating activities of hormones and enzymes.
Proteins are defined as chains of amino acids linked together.
Peptide bonds link those amino acid chains together.
Be aware of the difference between a growth hormone releasing hormone and a growth hormone releasing peptide.
Growth hormone releasing hormone (GHRH) – Manufactured by the pituitary gland, stimulates secretions of growth hormone.
Growth hormone releasing peptides (GHRP) – such as growth hormone releasing hexapeptide – stimulate increase of growth hormone secretagogues that stimulate the hypothalamus to secrete growth hormone.
A secretagogue is simply defined as a substance that stimulates secretions in the body.
Hormones have a huge influence on the body activities and interactions of other hormones manufactured in the body.
Injecting any type of hormone, including secretagogues into the body when it doesn’t need it can influence the body in negative ways. This is caused by disruption of otherwise normal balances and functions.
Any side effects caused by GHRP-6 are similar to what you would get from HGH injections.
This is because the main, purported effect that draws bodybuilders to GHRP-6 is a tremendous increase in the levels of HGH. Where synthetic HGH and GHRP-6 differ is that the HGH gotten from the use of GHRP-6 is the endogenous HGH produced by the body of humans.
Nonetheless, the side effects of GHRP-6 are basically side effects that happen as a result of using HGH, but there are side effects of GHRP-6 which are directly attributed to the peptide itself.
GHRP-6 is not held to be a sex-specific hormone, so it is wrong to view it the same way one would look at a steroid hormone like Dianabol.
The product is cycled by male and females alike without any worry of virilisation or androgenic side effects.
GHRP-6 side effects which stem from the elevation in HGH consist of joint pain, symptoms associated with the flu, carpal tunnel syndrome, water retention, bloating and headaches.
Side effects which have a slighter possibility of occurring include sore bones, numbness or tingling in the skin, dizziness, touch sensitivity reduction and enlarged male breast tissue (gynecomastia).
HGH mediates Estrogen and can contribute to the adverse effect of gynecomastia even though it is not a sex hormone. Those who use GHRP-6 or any other compound related to HGH with anabolic steroids that are aromatizable put themselves at a greater risk of this negative outcomes.
GHRPs are mild, but given these dangers, a milder first step might be deer antler products like AntlerX which some bodybuilders swear by.
For example, ghrelin is not just a hunger hormone that stimulates the appetite. It’s also been studied in regard to its potential to reduce inflammation, aid in healing processes, and promote thermogenesis or fat burning.
Bodybuilders or athletes using GHRP-6 and/or GHRP 2 or other types of growth hormone should be aware that testing methods for detection have improved in sports drug testing capabilities.
Hormone disruption increases risk of adverse side effects and reactions. Before trying to get GHRP-6 results, or from any form of growth hormone or secretagogue, take the time to research how they may affect the body: good and bad.Buy GHRP-6GhrhGHRP-6GHRP-6 CJC-1295GHRP-6 CreamGHRP-6 CycleGHRP-6 DosageGHRP-6 PeptideGHRP-6 ReviewsGHRP-6 Side EffectsGrowth Hormone Releasing HexapeptideGrowth Hormone Releasing HormoneHGH PeptidesPeg mgf PeptideSermorelin Ghrp2