(12 votos)
Loading ...
Growth hormone releasing hexapeptide is a hormone.
Users know it interchangeably as either a protein hormone or a peptide hormone.
It can also be labeled a Growth Hormone Releasing Peptide (GHRP), which is why it is also called GRHP-6.
GHRP-6 is a peptide or protein hormone that is made up of a 6 amino acids polypeptide chain.
The chain also contains unnatural D-amino acids synthetically created explicitly for the release of HGH from the pituitary gland, qualifying GHRP-6 as a proper HGH secretagogue.
It’s a mouthful, but a secretagogue is a substance that encourages or triggers release of something, neste caso, hormona de crecemento. Mercar HGH-X2 en liña aquí.
Táboa de contidos
Growth Hormone Releasing Hexapeptide Reviews
Before digging deeper into how growth hormone releasing hexapeptide works, é importante para entender polo menos o básico sobre a hormona do crecemento.
A hormona de crecemento producida no corpo é chamado somatotropina.
hormona de crecemento humano é fabricado na glándula prostática, que está situado no cerebro.
A glándula prostática é coñecida como o mestre glándula do corpo.
Isto é porque é responsable do mantemento e secrecións doutras hormonas incluíndo testosterona (fabricados nos testículos e as súas pequenas cantidades polos ovarios da muller) así como o factor de crecemento similar á insulina (fabricado no fígado).
Below are some summarized points about this GHRP.
- Prolactin and cortisol levels are less significantly increased by GHRP-6 when compared to GHRP-2
- For the maximum release of HGH from the pituitary gland, it is necessary to time the doses of GHRP-6 appropriately
- Administering Ghrelin mimetics like GHRP-6 together with GHRH can allow a greater HGH pulse from the pituitary gland than when GHRP-6 is used alone. There are synergetic effects of GHRP and GHRH analogues on the pituitary gland that can aid in increasing HGH release from the pituitary
traballar xuntos, hormona de crecemento humano (HGH), testosterona, e factor de crecemento similar á insulina son beneficiosos no crecemento e desenvolvemento de numerosos tecidos no organismo, máis notabelmente muscular – polo menos tanto como fisiculturismo están en cuestión.
Sintético ou hormona de crecemento de laboratorio fabricada (HGH) chámase somatropina.
hormona de crecemento sintético é frecuentemente utilizada en tratamentos médicos para os pacientes diagnosticados coa infancia ou a idade adulta de deficiencias da hormona de crecemento.
A hormona do crecemento ten un papel en máis que desenvolvemento muscular. Contribúe e está envolto:
- o crecemento do esqueleto ea densidade ósea
- metabolismo
- dixestión
A responsabilidade principal do crecemento da hormona de liberación da hormona producida de corpo (GHRH) é para estimular a secreción de hormona de crecemento.
O que é a diferenza entre o crecemento da hormona de liberación da hormona e un péptido de liberación da hormona de crecemento?
O que fai Growth hormona Releasing Hexapeptide Do?
Growth hormone releasing hexapeptide é un dos diversos secretagogos que estimulan a glándula prostática para liberar a hormona de crecemento.
o “hexapeptide” define un péptido de liberación da hormona de crecemento específico máis vulgarmente coñecido como o GHRP-6 (un péptido de seis lados). En termos médicos, it’s known as His-Dtrp-Ala-Trp-Dphe-Lys-NH2. [1]
O que é exactamente fai? It stimulates not only endogenous (producido corpo) growth hormone secretions, but can increase levels of insulin-like growth factor-1 (IGF-1 manufactured in the liver).
En escenarios de médicos, O GHRP-6 is commonly used to treat a number of growth hormone deficiencies, but it’s also effective in the treatment of some eating disorders, and muscle wasting scenarios (caquexia).
Como funciona?
Growth hormone releasing peptides not only increase secretions of growth hormone, but secretions of Ghrelin, coñecido como a “hormona da fame” to increase appetite – que fisiculturismo ou atletas deben ser conscientes de antes de usar.
Not to be confused with GHRH, GHRPs like Growth Hormone Releasing Hexapeptide interact with the hypothalamus’ and pituitary gland’s receptors that are different from those that GHRH interacts with.
The HGH secretagogue receptor, now commonly referred to as the Gherkin receptor, is stimulated by GHRP-6. GHRP-6 does not stimulate the GHRH receptor—that’s the job of Growth Hormone Releasing Hormones like CJC-1295 without DAC.
GHRP-6 stimulates an HGH pulsatile release from the pituitary gland. This is usually the strongest within the first 20-30 minutes and normally lasts for several hours.
The half-life of GHRP-6 ranges between 15 minutes and 60 actas.
Due to the ability of GHRP to stimulate the release of HGH from the pituitary gland, the effects from GHRP-6 can be the same as the effects of synthetic HGH administered for a longer time.
But with GHRP-6, the time that the HGH remains in the bloodstream is less than the time that synthetic HGH will remain circulated.
The amount of HGH in the bloodstream is maintained for a few hours, but the most significant HGH blood plasma levels are achieved within the first 30 minutes of administering GHRP-6.
This is the reason why physique builder recommend administering GHRP at multiple times during the day to maintain steady and high HGH levels.
The HGH effects from the utilization of GHRP-6 can include increased muscle mass, reduced body fat, aumento da resistencia, improved sleep quality, increased rate of healing, increased strength and increased health and general well-being.
GHRP-6 Efectos secundarios
Antes do uso de GHRP-6, fisiculturismo e atletas debe ser consciente de que poñendo unha hormona ou un composto para o corpo que pode producir, romper, ou doutro xeito influír a produción hormonal normal e secrecións non arriscar o potencial de efectos secundarios inesperados.
recomendacións de dosificación varían dependendo de como se usa e que o atleta ou fisiculturismo espera del.
Most of the side effects are related to HGH, since ramping up endogenous production of this hormone if the main effect of GHRP-6.
HGH side effects can include headaches, hipoglicemia, síndrome do túnel do carpo, and flu-like nausea.
GHRP-6 has been linked with a host of side effects unique to GHRP-6 itself.
This is in addition to the possible side effects which are as a result of the elevation in HGH. Some of these side effects consist of the following:
mamilos lactantes:
Enhanced Prolactin section is also included as a side effect of GHRP-6. This can lead to lactating nipples.
This is not a common occurrence, but it can occur in individuals who are sensitive. GHRP-6 shows the capacity to cause secretion of Prolactin and Cortisol, but other studies have indicated that the increase of Cortisol and Prolactin in a majority of the test subjects did not show any changes at 100mcg GHRP-6 doses or lower.
Doses higher than 100mcg are said to elevate the secretion of prolactin, if only slightly. At these minimal levels, there is less possibility of lactation occurring.
non obstante, there have been reports of lactation from some users which can either be the result of too many elevated doses of GHRP-6 or of a pre-existing sensitivity.
Bodybuilders address the issue of excess prolactin through a prolactin adversary like Bromocriptine, Cabergoline, Vitamin B6 or Pramipexole.
mareo & Light-headedness:
GHRP-6 have been reported to lead to “head rushes” followed by a sharp pain which can feel like needles and pins.
Physique builders who have experienced this adverse reaction report that the pain can be quite severe. This effect may also come as a spell of light-headedness or dizziness.
This effect is broadly understood to be a signal that the pituitary gland is being stimulated by the peptide, and it is a side effect associated with most HGH secretagogues.
Chronic stimulation of hunger:
Dun modo xeral, GHRPs will cause hunger because they mirror the actions of the body’s hormone Ghrelin. This side effect has been proven both clinically and anecdotally to be the most pronounced with GHRP-6 when compared to all other GHRPs.
GHRP-6 has the tendency to generate an intensity of appetite that is frequently described as “painful hunger,” and this effect is commonly confused as an episode of hypoglycemia.
The hunger resulting from the use of GHRP-6 is basically the peptide reacting to the receptors of Ghrelin which communicate hunger to different areas of the brain.
There is no anecdotal evidence or study which shows the readouts if hypoglycemic blood glucose following the administration if GHRP-6.
The hunger is widely known to subside after a meal. There have also been reports from various users that the hunger intensity vanished many weeks into the cycles of GHRP, without vanishing totally.
GHRP-6 Venta
Antes de mercar calquera fabricante, ser consciente de que eles non son xeralmente pronto dispoñible a venda desde farmacéutica respectable ou empresas de investigación de produtos químicos.
Este é, sen previa autorización para a compra dunha institución sanitaria ou profesional.
Podes atopar avisos que estado “este producto está destinado como un produto químico de investigación única”.
Unha serie de empresas farmacéuticas e de investigación peptídico falso para facer vender unha variedade de produtos de peptídicos para fisiculturismo e atletas. Un fabricante popular, vende 10 mg GHRP-6 por aproximadamente $30 por bote.
Bodybuilders tamén deben ser conscientes das prácticas de etiquetado defectuosos e enganosa. A adquisición dun bote que reivindica 99% pureza dun laboratorio subterráneo non proba necesariamente certo en todos os casos.
Recomendacións de dosificación de GHRH-6
Doses recomendadas para a hormona de crecemento e secretagogos varía moito dependendo usuarios.
xeralmente, de dosificación para o uso da hormona do crecemento hexapéptido liberando medias 1 mcg por kg de peso corporal, aínda que algúns fisiculturismo comezar 100 mcg por dose, con independencia do peso.
O aumento da dosificación deste tipo de péptido da hormona pode realmente diminuír a súa eficacia, xa que os receptores de • grelina • (que é o que GHRP-6 obxectivos) xa está completamente saturada no 100 nivel mcg.
En calquera dosificación, prestar atención para efectos secundarios. A dieta é importante en relación á eficacia.
Recoméndase que a dosificación siga polo menos dúas horas de espera despois do consumo dunha comida ou non antes de, aproximadamente, 30 minutos antes de comer unha comida que contén graxas son carbohidratos, que son percibidas para reducir a secreción de hormona de crecemento humano.
Nota – hormona de crecemento humano é liberada pola glándula prostática por medio de impulsos ao longo do día, máis eficaz á noite durante o sono.
A fin de manter unha liberación constante de algo de HGH ao usar libera hormona de crecemento hexapéptido, experienced users recommend dosages averaging three hours apart or:
- 100 mcg upon waking
- 100 mcg post-workout
- 100 mcg in the evening before bed
Some bodybuilders inject twice-daily while others inject more frequently. Growth hormone releasing hexapeptide results are not immediate and can take several weeks for observable changes to be noticed.
Does Sermorelin Work ReviewsGhrhGhrp 6 PeptideHormona do Crecemento Releasing HexapeptideGrowth hormona Releasing hormonaHGH PeptidesHuman Growth FactorIncrelexMecaserminMod Grf 1 29Peg mgf DosagePeg mgf PeptidePeg mgf ResultsFactor de crecemento de Mecano peguiladoSermorelin Ghrp2Referencias
- Mallo F, Alvarez C.V., Benitex L, Burguera B, Coya R, Casanueva F.F., Diéguez C. Refulation of His-dTrp-Ala-Trp-dPhe-Lys-NH2 (O GHRP-6) Induced GH Secretion in the Rat. neuroendocrinologia 1993;57:247–256 https://doi.org/10.1159/000126366
- Peyreigne C, Bouix D, Micallef JP, J Mercier, Bringer J, Préfaut C, marrón JF. Exercise-induced growth hormone secretion and hemorheology during exercise in elite athletes. Cline Hemorheol Microcirc. 1998 outubro;19(2):169-76. No resumo dispoñible.
- Hoffman JR, Kraemer WJ, Bhasin S, Storer T, Ratamess NA, Haff GG, Willoughby DS, violación AD. Posición estar Andróxenos e uso de hormona de crecemento humano. J Forza condici Res. 2009 agosto;23(5 suppl):S1-S59. doi: 10.1519/JSC.0b013e31819df2e6. revisión. errata na: J Forza condici Res. 2010 febreiro;24(2):585.
- Holt RI, Bassett EE, Erotokritou-Mulligan I, McHugh C, Cowan D, Bartlett C, Sönksen PH; GH-2004 group.. Movendo-se a un paso de captura as fraudes GH: A experiencia GH-2004. Crecemento Horm IGF Res. 2009 agosto;19(4):346-51. doi: 10.1016/j.ghir.2009.04.012.
- Higuti E, Cecchi CR, Oliveira NA, Vieira DP, Jensen TG, Jorge AA, Bartolini P, Peroni NC. as respostas de crecemento tras unha única administración intra-muscular plásmido hGH en comparación con inxeccións diarias de HGH en ratinhos anano. Curro Gene ther. 2012 decembro;12(6):437-43.
- Bidlingmaier M, Suhr J, Ernst A, Wu Z, A Keller, Strasburger CJ, Bergmann A. imunoensaios de alta sensibilidade de quimiluminescência para a detección de hormona de crecemento dopagem en deportes. Cline Chem. 2009 romper;55(3):445-53. doi: 10.1373/clinchem.2008.112458.
- Abellan R, Ventura R, Palmi I, Charles S, Bacosi A, Bellver M, Olive R, JA Pascual, Pacifici R, seguro J, Zuccaro P, Pichini S. Immunoassays for the measurement of IGF-II, A IGFBP-2 e -3, e ICTP biomarcadores como indirectos da recombinante mal uso da hormona de crecemento humano no deporte. Valores en poboación seleccionada de atletas. J Pharm Biomed Anal. 2008 novembro 4;48(3):844-52. doi: 10.1016/j.jpba.2008.05.037.
- Erotokritou-Mulligan I, Bassett EE, Bartlett C, Cowan D, McHugh C, Seah R, Curtis B, Wells V, Harrison K, Sönksen PH, Holt RI; GH-2004 Grupo.. O efecto da lesión deportiva no insulina-like growth factor-I e tipo 3 procolágeno: implicacións para detección de crecemento abuso hormona en atletas. J Cline Endocrinol metab. 2008 xullo;93(7):2760-3. doi: 10.1210/jc.2007-2801.
- Stokes K. respostas hormona de crecemento para sub-máxima e exercicio de Sprint. Crecemento Horm IGF Res. 2003 outubro;13(5):225-38. revisión.
- Marcell TJ, Taaffe DR, Hawkins SA, Tarpenning KM, Pyka G, Kohlmeier L, Wiswell RA, Marcus R. arginina por vía oral non estimular basal ou aumentar a secreción de GH inducida por exercicio tanto en adultos novos ou maiores. J Gerontol Un Biol Sci Med Sci. 1999 agosto;54(8):M395-9.
- Hymer WC, Kraemer WJ, Nindl BC, Marx DO, Benson, Welsch JR, Mazzetti SA, Volek JS, Deaver DR. Características da circulación da hormona do crecemento en mulleres tras exercicios de resistencia aguda abondo. Am J Physiol Endocrinol metab. 2001 outubro;281(4):E878-87.
- Lawrence CB et ai. Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers. endocrinoloxía. 2002 Xan 1;143(1):155-62.
- Giustina A, Veldhuis JD. Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human. Endocrine reviews. 1998 decembro;19(6):717-97.
- Shimon I et ai. Human fetal pituitary expresses functional growth hormone-releasing peptide receptors. The Journal of Clinical Endocrinology & metabolismo. 1998 Xan 1;83(1):174-8.
- Popovic V et ai. The impact of cranial irradiation on GH responsiveness to GHRH plus GH-releasing peptide-6. The Journal of Clinical Endocrinology & metabolismo. 2002 maio 1;87(5):2095-9.
