A trial study of Nandrolone Decanoate was led by four scientists for Breast Cancer Research.
They started their study in 1980 and continue to perform randomized trials.
The first of which involved 98 women with advanced-stage breast cancer in their postmenopausal stage of life.
They were divided up into two groups of 49.
The first group consisted of patients to be treated with a drug called Tamoxifen and the other 49 were treated with Tamoxifen and Nandrolone Decanoate (brand name being Deca Durabolin). Buy Decaduro online here.
Table of Contents
This trial involved the analytical comparison of the 49 advanced-stage breast cancer patients being treated with Tamoxifen only.
Compared with the 49 advanced-stage breast cancer patients who were treated with the combination of Tamoxifen and Nandrolone Decanoate.
The first group of 49, after an unspecified amount of time being treated by Tamoxifen, had a measured response rate to this medicine at 49 percent.
The second 49 women in the study who were being treated with the combination of Tamoxifen and Nandrolone Decanoate had a response rate of only 45 percent, a bit lower than with Tamoxifen alone.
The determinate analysis indicated that each group’s response to treatment was not that much different between the two groups.
Each of the 98 patients suffered no significant Nandrolone Decanoate side effects and was tolerant of the drugs given to them for treatment.
Although the side effects from taking one or both of the pharmaceutical drugs were well tolerated by the 98 advanced-stage breast cancer patients.
This does not mean that there were absolutely no side effects from being exposed to the drugs and their potential for negative results.
It just warrants the indications that what side effects were experienced by these patients.
Whether they were taking Tamoxifen or a combination of Tamoxifen and the anabolic steroid, Deca Durabolin, were mild at their worst and did not require any of the 98 total patients to be withdrawn from the study.
Deca Durabolin and Kidney Problems
There are various studies that show a direct relation between kidney damage and the use of Deca Durabolin. A ten-year study conducted by the researchers at the Columbia University revealed that long-term use of Deca Durabolin can result in serious kidney damage.
This study was presented at the American Society of Nephrology during 2009. It was conducted on one power-lifter and nine bodybuilders. The common thing among them was that all of them were steroid users and every single one of them received permanent kidney damage.
Nine out of the ten subjects developed Focal Segmental Glomerulosclerosis, which is an irreversible kidney disease. This disease mainly attacks the glomeruli and damages them through scarring.
Glomeruli play the role of kidneys filtering units. Due to the fact that they cannot be regenerated, the Focal Segmental Glomerulosclerosis damages them.
However, there are certain protective measures that one can take during the anabolic cycle so that kidneys could be protected.
If a person is consuming Deca Durabolin then he must drink plenty of natural water, cut off the alcohol, avoid caffeine in any form, avoid eating the high protein meat diet, avoid consuming too much salt, quit smoking and get proper sleep.
He must also monitor his urine patterns and urine texture closely and if he any senses any sort of changes in them then he must instantly stop using Deca Durabolin and contact his doctor.
Deca Durabolin and Testosterone Suppression
Testosterone suppression is one of the worst after-effects caused by the use of Deca Durabolin.
Athletes or bodybuilders that use anabolic steroids often start experiencing a significant decrease in their endogenous testosterone production.
As a result of this effect, men may experience erectile dysfunction. This erectile dysfunction caused due to the use of Deca Durabolin is commonly known as “Deca Dick” and has affected a large number of bodybuilders.
To regain natural testosterone production and hormone levels, users should engage with a PCT after their cycle.
A study was recently conducted in Karolinska Institute in Sweden where the effects of Deca Durabolin were evaluated on twenty-one male users and their recovery after the use of steroids. All twenty-one subjects were detected through an anti-doping hotline set up.
Before they were included in the study, all twenty-one of the subjects confirmed to the researchers that they are determined to stop the use of Deca Durabolin. The biggest issue with Deca Durabolin is that stays in the users’ blood for almost 12 to 16 months post the cycle.
When the Swedish researchers took the first test of the Deca Durabolin users, their urine results revealed the concentration of 19-norandrosterone.
These subjects were again tested after six months and at that time their urine tests revealed the presence of 80% Nandrolone metabolites.
They were again tested after twelve months and even after that time almost 50% of them tested positive for Nandrolone. It means that getting rid of the effects of Deca Durabolin can be difficult.
Deca Durabolin and Heart Problems
If Deca Durabolin is used in heavy doses for long periods of time then it can result in heart attack. It has been suggested by various researchers that Nandrolone causes severe damage to the blood vessels, which increases the risk of heart failure.
Researchers have confirmed that prolonged use of anabolic steroids may result in fatal heart issues. These steroids result in cardiomegaly, which is basically the disease of heart enlargement.
The continued use of Deca Durabolin also leads to an increased count of red blood cells and blood clotting which elevates the blood pressure and may result in a heart attack. Anabolic steroids incur direct effects on the blood cells as they kill the heart cells and cause the walls of blood vessels to become thin.
Tamoxifen, a common pharmaceutical drug used to treat some forms of breast carcinoma, or what is more commonly known as cancer, gynecomastia in men (enlargement of breast tissue) and breast or pancreatic neoplasm.
It has two brand names associated with it, one of which is Nolvadex, while the other is Soltamox.
Tamoxifen is used primarily by oncologists in its estrogen antagonist form (as opposed to its other formulated design as an estrogen agonist).
Nandrolone Decanoate, or what is usually referred by as the official brand name, Deca Durabolin, and also what is known in the athletic and bodybuilder universe as simply “Deca”.
It does come with some risk as an injection and even holds some risk of side effects when administered as an oral form, or capsule.
Some potential, yet rarely reported side effects with the drug, Tamoxifen, are:
These, and other related side effects from the drug, are all due to the medicine’s baseline usage for the blocking the female hormone, estrogen and some of the negative effects excess estrogen can have on the body, such as breast cancer.
On the other hand, Nandrolone Decanoate has a greater potential for negative side effects to be experienced by users and medical patients alike.
This is especially true in women who expose themselves to the drug for whatever reason, whether for medical purposes or recreational, such as with athletes.
Women who take the drug, which is a derivative of 19-nor testosterone, increase their risk of developing virile side effects such as a deepening of the voice, body hair growth and excess facial hair growth.
That’s why women are better off trying Winstrol for lower side effects because the risks are too high with Deca.
A 2005 medical trial study involving nine men with the HIV virus consisted of orally administering 400 mg of Megestrol Acetate once per day.
This was given along with 100 mg of Nandrolone Decanoate via intramuscular injection once every 15 days during a 16-week cycle.
Before, during and after the trial study, the nine HIV-infected men were analyzed for fat mass, muscle strength, circumference of upper arms, and measurement of skin folds.
Because of the data collected before and during the 16-week study, it was determined that the men had significantly increased in body weight and muscle strength with only a few having experienced noticeable side effects.
Some of the side effects included one mild case of Gynecomastia, or breast tissue enlargement and four cases of asymptomatic adrenal suppression.
While all experienced a lowering of testosterone serum levels, only four experienced levels that fell below normal levels.
In Sydney, Australia, a 16-week trial study was held by several HIV/AIDS ambulatory specialists within private and public sectors of the industry.
Of 220 pre-study phase applicants, 24 men infected with HIV/AIDS, 11 percent of the 220, had gone on to officially participate in the trial study due to weight-gain failure during the pre-study phase.
Seventeen of the 24 men in the study actually completed the 16 weeks after being injected intramuscularly once every two weeks by professional administers.
The study, in the end, had determined the conclusion and beneficial price that the use of Nandrolone Decanoate had on the patients for wasting associated with the HIV virus.
It was significantly beneficial to those suffering from body wasting from the virus. These injections added much needed lean body mass and greatly improved the body’s functioning.
Overall, the medical use of this controversial anabolic steroid, Nandrolone Decanoate or Deca Durabolin, provides conclusive evidence for the significant improvement of quality of life in patients suffering from degenerative body and bone mass issues due to disease and postmenopausal related symptoms.