It is a term that was often used interchangeably for a number of growth hormones.
Somatrem is available by prescription in some countries around the world, depending on manufacturer availability.
Additional brand name growth hormones include:
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Somatrem is defined as a biosynthetic, single polypeptide chain that contains 192 amino acids.
Endogenous growth hormone contains 191 amino acids. The additional amino acid is called methionine.
Somatrem is an analog of naturally produced growth hormone.
An analog is defined as a substance that mimics or is similar to something else.
Growth hormone is manufactured in the body by the pituitary gland.
In cases where the pituitary gland malfunctions or does not produce adequate amounts of growth hormone, growth hormone therapy may be recommended.
In a laboratory environment, Somatrem is created utilizing recombinant DNA (rDNA) technology through modification of a bacteria known as Escherichia coli (E.coli).
Recombinant human growth hormone is defined as somatropin, but dozens of brands and generic terms apply to this type of synthetic, laboratory produced growth hormone.
Recombinant DNA technology takes genetic materials from different sources. This “recombining” takes strands from two different DNA sources and combines them together.
Its primary mechanism of action was to stimulate linear bone growth.
It’s also promoted to have the potential to increase muscle cells, growth of organs cells, and promote erythropoiesis or production of red blood cells.
Growth hormone like Somatrem also has the potential for influencing metabolism of:
Somatrem belongs to the category of growth hormone used to treat growth failure caused by a number of issues including defective pituitary gland function.
Use by bodybuilders and athletes who turn to growth hormone to improve physique, increase and maintain muscle mass, and as a weight-loss product is not recommended.
Even in medical situations under careful supervision by a physician, growth hormone has the potential to cause side effects.
This is especially true when used by someone who doesn’t need growth hormone.
Hormone levels in the body are carefully balanced, with one hormone often affecting another.
Growth hormone does have the potential to provide benefits for bone and muscle growth development in children and adults deficient in growth hormone, but the benefits are often outweighed by the potential for side effects.
This is why many older forms of growth hormone have been discontinued and replaced with newer drugs.
Some of the most common side effects associated with synthetic growth hormone like Somatrem include but are not limited to:
More serious reactions to synthetic growth hormone are not readily visible but can affect overall health and wellness.
Because Somatrem and other growth hormone products can interfere with metabolic function, it can negatively increase levels of “bad” or low-density lipoprotein known as LDL cholesterol.
Increased levels of low-density lipoprotein over that of the good cholesterol (high-density lipoprotein/HDL) can cause cardiovascular damage, hardening of the arteries, and an increased risk for heart attack or stroke.
Developing diabetes is also possible due to Somatrem and other growth hormone’s impact on metabolism and the body’s blood sugar levels.
Use of Somatrem, other growth hormone products, or variations thereof are not recommended for men or women with otherwise normal pituitary gland function.
Disrupting hormone levels not only contributes to serious side effects, but it can take months to achieve normal balances once the drug is discontinued.
Excessive cellular growth of bone, muscle, and conduct of tissues is one of the more danger is aspects of non-supervised use of growth hormone.
Using Somatrem or any other form of somatropin or growth hormone supplementation requires careful consideration in regard to short-term and long-term safety.