Zorbtive is a brand name form of synthetic growth hormone (somatropin).
It’s a prescription-only drug typically recommended in the treatment of short bowel syndrome.
It is not recommended for usage in someone with otherwise normal hormone function and balances.
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Zorbtive is a synthetic form of human growth hormone manufactured in a laboratory environment that utilizes recombinant DNA (rDNA) technology.
Like endogenous or body-produced human growth hormone – hGH – it contains 191 amino acids.
Zorbtive is manufactured by modifying a mouse cell line (C127 ) that, through the insertion of the HGH gene.
It has been modified to create an identical structure and amino acid sequence as that created by the human pituitary gland, located in the brain.
Its main mechanism of action is to act as a tissue building and anti-catabolic product that has an ability to target receptors of specific cellular types that can encourage growth.
This function is triggered by the presence of insulin-like growth factor-1 (IGF-I).
As mentioned, Zorbtive is mainly relegated to treatment of short bowel syndrome (Nutrestore is another alternative for SBS), but as with other forms of growth hormone, does provide additional benefits:
Zorbtive, like other synthetic growth hormones, can have a number of side effects.
For a patient diagnosed with short bowel syndrome and requiring parenteral or tube feeding for nutritional support, the hormone is considered relatively safe.
Used by bodybuilders, dosages are often much higher than those recommended in medical treatments. High doses can contribute to an increased risk of side effects and adverse reactions.
Zorbtive, manufactured by Merck, is a prescription-only drug. It comes in 8.8 mg vials. Each vial of Zorbtive contains:
Zorbtive is not typically available as a pharmaceutical drug in everyday environments.
Bodybuilders intending to use it must often turn to black-market resources or underground labs operating without a license or certification.
This approach to buying the drug comes with obvious risks to users. Bottom line: use caution.
Medical scenario dosages (for short bowel syndrome) start at 0.1 mg per kilogram to 8 mg maximum on a daily basis.
Bodybuilders are known for typically taking higher than recommended dosage of most prescription strength drugs, which increases risk.
Like any other hormone introduced in the body, Zorbtive can trigger a number of side effects.
Side effects are possible even with medically condoned and supervised usage.
When used without a prescription or physician oversight, the risk of danger increases.
Zorbtive has been linked to incidents of pancreatitis or inflammation of the pancreas. This can cause sudden and sharp pain in the abdominal region.
Changes in metabolic functions such as glucose manufacture and usage are also possible, and not in a good way.
Synthetic forms of growth hormone have been linked to glucose intolerance, development of Type 2 diabetes mellitus or worsening conditions of diabetes mellitus.
Such indications have been noted in the realm of medical supervision as well.
A number of adverse reactions have been noted by the Food and Drug Administration, including but not limited to:
Other negative reactions can occur in numerous body systems including:
Before resorting to synthetic growth hormone products like Zomacton, Serostim, Saizen, Gattex, or Tev-Tropin to enhance muscle growth and overall body physique enhancement, be aware of how the drug behaves in the body.
Refer to the manufacturer’s website and the Zorbtive package insert for more information.
Access bodybuilding forum boards to learn how others have used the drug and its benefits and/or side effects – but be wary – these suggestions are not always safe.
Zorbtive can have a huge influence on other hormones in the body beside that of growth hormone manufactured in the pituitary gland, or insulin-like growth factor-1, manufactured and secreted by the liver.
It should be noted that many of the side effects of somatropin in medical scenarios are relatively rare, although they can happen.
Using the drug and higher than recommended dosages can increase the risk of adverse reactions. Bodybuilders considering use of Zorbtive should proceed with caution.